D-Tubocurarine chloride

CAS: 57-94-3

Ref. 3D-FT65013

Product Information

• Name: D-Tubocurarine chloride
• Synonyms: (+)-Tubocurarine, (+)-Tubocurarine dichloride, (+)-Tubocurarine hydrochloride, 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, chloride, hydrochloride (1:1:1), (13aR,25aS)-, 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, chloride, hydrochloride, (13aR,25aS)-, 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, chloride, hydrochloride, [13aR-(13aR*,25aS*)]-, 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3′,2′:14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, tubocuraranium deriv., 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3′,2′:14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, chloride, hydrochloride (1:1:1), (13aR,25aS)-, 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3′,2′:14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, chloride, hydrochloride, (13aR,25aS)-, 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3′,2′:14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, chloride, hydrochloride, [13aR-(13aR*,25aS*)]-, 6,6'-Dimethoxy-2,2',2'-Trimethyltubocuraran-2'-Ium-7',12'-Diol Chloride, 7',12'-Dihydroxy-6,6'-Dimethoxy-2,2',2'-Trimethyltubocuraran-2,2'-Diium Dichloride, <span class="text-smallcaps">D</span>-Tubocurarine, Amelizol, Amerizol, Chlorure De Tubocurarine, Cloruro De Tubocurarina, Curarin HAF, Delacurarine, Dextrotubocurarine chloride, Intocostrine T, Introcostrin, Tubadil, Tubarine, Tubocuraranium, 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, chloride, hydrochloride, Tubocuraranium, 7′,12′-dihydroxy-6,6′-dimethoxy-2,2′,2′-trimethyl-, chloride, hydrochloride, Tubocurarinchlorid, Tubocurarine Chloride, Tubocurarine, chloride, hydrochloride, (+)-, d-(+)-Tubocurarine chloride, d-Paracurarine chloride, d-Tubocurarine, d-Tubocurarine dichloride, d-Tubocurarine hydrochloride
• CAS: 57-94-3

Description

D-Tubocurarine chloride is a model system for the study of neurotoxicity. It binds to the α1 subunit of the nicotinic acetylcholine receptor, which is found in neuronal membranes. D-Tubocurarine chloride has been shown to have low potency, with whole-cell recordings showing that it does not cause neuronal death but rather generates a low level of paralysis. D-Tubocurarine chloride inhibits the release of neurotrophic factors and can be used as a pharmacological treatment for bowel disease. This drug has also been shown to block the binding of benzalkonium chloride and bisbenzylisoquinoline alkaloids to x-ray crystal structures, which may be due to its similarity to these compounds.

• Brand: Biosynth

Chemical properties

• Molecular weight: 681.64 g/mol
• Formula: C₃₇H₄₂Cl₂N₂O₆
• Purity: Min. 95%
• Color/Form: Powder