Thiacetazone

CAS: 104-06-3

Ref. 3D-FT65183

Product Information

• Name: Thiacetazone
• Synonyms: 4'-Formylacetanilide thiosemicarbazone, 4-Acetylaminobenzaldehyde thiosemicarbazone, 4207Rp, Acetamide, N-[4-[[(aminothioxomethyl)hydrazono]methyl]phenyl]-, Acetamide, N-[4-[[2-(aminothioxomethyl)hydrazinylidene]methyl]phenyl]-, Acetanilide, 4′-formyl-, 4′-(thiosemicarbazone), Acetanilide, 4′-formyl-, thiosemicarbazone, Aktivan, Ambathizon, Amithiozone, Amitiozon, Antib, Benthiozone, Benzothiozane, Benzothiozon, Berculon A, Berkazon, Conteben, Diasan, Diazan, Diazane, Domakol, Ilbion, Livazone, Mirizone Neustab, Mivizon, Myvizone, N-[4-(carbamothioylcarbonohydrazonoyl)phenyl]acetamide, N-[4-[[2-(Aminothioxomethyl)hydrazinylidene]methyl]phenyl]acetamide, N-{4-[(E)-(2-carbamothioylhydrazinylidene)methyl]phenyl}acetamide, NSC 3550, Neotibil, Neustab, Novakol, Nuclon argentinian, Panrone, Parazone, Sdt 1041, Seroden, Siocarbazone, Sq 2321, Tb I/698, Tebalon, Tebecure, Tebemar, Tebesone I, Tebethion, Tebethione, Tebezon, Thiacetone, Thiacetozone, Thibon, Thibone, Thioacetazon, Thioazetazone, Thiocarbazil, Thiocarbazyl, Thiomicid, Thionicid, Thioparamizon, Thioparamizone, Thiosemicarbazone, Thiosemicarbazone (pharmaceutical), Thiotebesin, Thiotebezin, Thiotebicina, Thizone, Tiacetazon, Tibicur, Tibion, Tibione, Tibizan, Tibon, Tibone, Tioacetazon, Tioatsetazon, Tiobicina, Tiocarone, Tiosecolo, Tubercazon, Tubigal, Tubin, p-Acetamidobenzaldehyde thiosemicarbazone, p-Acetaminobenzylidenethiosemicarbazone, p-Acetoaminobenzaldehyde thiosemicarbazone, p-Acetylaminobenzaldehyde thiosemicarbazone, p-Formylacetanilide-3-thiosemicarbazone
• CAS: 104-06-3

Description

Thiacetazone is a topical antimicrobial agent that inhibits the growth of microorganisms by altering the mitochondrial membrane potential. It has been shown to inhibit the production of reactive oxygen species and lipid peroxidation, which are important factors in the development of toxic epidermal necrolysis and other skin disorders. Thiacetazone has also been shown to have antimicrobial activity against bacteria, fungi, and viruses. This drug is used as an ingredient in combination preparations for the treatment of infectious diseases, such as HIV infection. Thiacetazone is active against resistant mutants with a body mass index (BMI) greater than or equal to 25 kg/m2.

• Brand: Biosynth

Chemical properties

• Molecular weight: 236.29 g/mol
• Formula: C₁₀H₁₂N₄OS
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H12N4OS/c1-7(15)13-9-4-2-8(3-5-9)6-12-14-10(11)16/h2-6H,1H3,(H,13,15)(H3,11,14,16)/b12-6+
• InChI key: InChIKey=SRVJKTDHMYAMHA-WUXMJOGZSA-N
• SMILES: CC(=O)Nc1ccc(/C=N/NC(N)=S)cc1