Triptophenolide

CAS: 74285-86-2

Ref. 3D-FT65732

Product Information

• Name: Triptophenolide
• Synonyms: Hypolide
• Brand: Biosynth
• Description: Triptophenolide is a bioactive compound, which is a diterpenoid lactone extracted from the plant Tripterygium wilfordii. This compound is characterized by its ability to modulate various molecular targets and pathways associated with inflammation and immune response. The mode of action of triptophenolide involves the inhibition of nuclear factor kappa B (NF-κB) signaling, a pivotal transcription factor that regulates genes involved in inflammation, immunity, cell proliferation, and survival. By disrupting NF-κB activity, triptophenolide effectively decreases the expression of pro-inflammatory cytokines and other mediators.

Chemical properties

• Molecular weight: 312.4 g/mol
• Formula: C₂₀H₂₄O₃
• Purity: Min. 95%