6,7,8-Trimethoxycoumarin

CAS: 6035-49-0

Ref. 3D-FT65839

Product Information

• Name: 6,7,8-Trimethoxycoumarin
• Synonyms: o,o-Dimethylfraxetin, 2H-1-Benzopyran-2-one, 5,6,7-trimethoxy-, 2H-1-Benzopyran-2-one, 6,7,8-trimethoxy-, 5,6,7-Trimethoxycoumarin, 6,7,8-Trimethoxy-2H-1-benzopyran-2-one, 6,7,8-Trimethoxy-2H-benzopyran-2-one, 7,8,9-Trimethoxycoumarin, Coumarin, 6,7,8-trimethoxy-, Dimethylfraxetin, Fraxetin dimethyl ether

Description

6,7,8-Trimethoxycoumarin is a coumarin derivative that inhibits melanogenesis and has been shown to have anticancer activity. It has also been found to bind to the CB2 receptor and induce immunomodulatory effects. 6,7,8-Trimethoxycoumarin has shown antiinflammatory properties by inhibiting prostaglandin synthesis in the human erythroleukemia cell line K562. This coumarin derivative also inhibits the replication of both DNA and RNA. 6,7,8-Trimethoxycoumarin inhibits protein synthesis by binding to ribosomes and blocking the binding of aminoacyl-tRNA to them. It also binds to phenolic acid receptors on cells in culture.

• Brand: Biosynth

Chemical properties

• Molecular weight: 236.22 g/mol
• Formula: C₁₂H₁₂O₅
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3
• InChI key: InChIKey=RAYQKHLZHPFYEJ-UHFFFAOYSA-N
• SMILES: COc1cc2ccc(=O)oc2c(OC)c1OC