(+/-)-Trans-1,2-diaminocyclohexane

CAS: 1121-22-8

Ref. 3D-FT76176

Product Information

• Name: (+/-)-Trans-1,2-diaminocyclohexane
• Synonyms: (+/-)-trans-1,2-Cyclohexanediamine, (1R,2R)-rel-1,2-Cyclohexanediamine, (1S,2S)-cyclohexane-1,2-diamine, 1,2-Cyclohexanediamine, (1R,2R)-rel-, 1,2-Cyclohexanediamine, trans-, 1,2-trans-Diaminocyclohexane, Cyclohexane-1,2-Diamine, S,S-Cyclohexanediamine, Trans-(L)-1,2-Diaminecyclohexane, rel-(1R,2R)-1,2-Cyclohexanediamine, rel-(1R,2R)-Cyclohexane-1,2-diamine, trans-N,N′-1,2-Cyclohexanediamine, trans-dl-1,2-Diaminocyclohexane
• CAS: 1121-22-8

Description

(+/-)-Trans-1,2-diaminocyclohexane is a chiral compound that is used in the preparation of anticancer drugs. It has been shown to inhibit cancer cell lines in a linear regression analysis and inhibits tumor growth by chelating copper ions. The 5-membered ring of the molecule forms hydrogen bonding interactions with the 3-mercaptopropionic acid. (+/-)-Trans-1,2-diaminocyclohexane binds to DNA through its chloride group and inhibits DNA synthesis by reacting with amino groups on the phosphate backbone of DNA. This reaction leads to formation of a stable covalent intermediate between (+/-)-trans-1,2-diaminocyclohexane and the 5' phosphate group on one strand of DNA. This inhibition results in decreased levels of cyclohexane ring, which prevents tumor growth.

• Brand: Biosynth

Chemical properties

• Molecular weight: 114.19 g/mol
• Formula: C₆H₁₄N₂
• Purity: Min. 95%
• Color/Form: Colorless Clear Liquid