Umbellatin

CAS: 316-41-6

Ref. 3D-FU70620

Product Information

• Name: Umbellatin
• Synonyms: Berberine sulphate, 5,6-Dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium sulfate, Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate (2:1), Berberine sulfate (2:1), Berberine, sulfate, Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, sulfate (1:1), Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, sulfate (2:1), Bis(9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium) sulfate, Bis(9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium) sulfate, Neutral berberine sulfate

Description

Umbellatin is a natural compound that has been shown to have antimicrobial activity against a variety of microorganisms. It was found to inhibit the growth of infectious pathogens, such as Staphylococcus aureus, Streptococcus pyogenes and Escherichia coli. The mechanism of action of umbellatin is not yet fully understood but it has been proposed that it may inhibit the synthesis of bacterial DNA by binding to the enzyme polymerase chain reaction (PCR). This hypothesis is supported by experiments which showed that berberine also inhibits PCR. Umbellatin also shows synergistic effects when combined with basic fibroblast growth factor (bFGF) in skin tumor formation in mice. In addition, umbellatin has been shown to prevent hepatic steatosis in animals and has been proposed for treatment of metabolic disorders.

• Brand: Biosynth

Chemical properties

• Molecular weight: 768.79 g/mol
• Formula: C₄₀H₃₆N₂O₁₂S·xH₂O
• Purity: Min. 95%
• Color/Form: Powder