Veratric acid

CAS: 93-07-2

Ref. 3D-FV28690

Product Information

• Name: Veratric acid
• Synonyms: 3,4-Dimethoxybenzoic acidDimethylprotocatechuic acidNSC 7721, 3,4-Bis(methyloxy)benzoic acid, 3,4-Dimethoxybenzoate, Acide veratrique, Acido Veratrico, Benzoic acid, 3,4-dimethoxy-, Dimethylprotocatechuic acid, Nsc 7721, Veratrumsaure

Description

Veratric acid is a natural compound that is found in plants such as Vitis vinifera and Vaccinium myrtillus. It has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae. Veratric acid binds to toll-like receptor 4 (TLR4), which activates the transcription factor nuclear factor kappa B (NF-κB) and increases expression of bacterial genes. It also inhibits pro-inflammatory cytokines by preventing the acetylation of histones at position H3, which are involved in transcriptional regulation. Veratric acid has synergistic effects when combined with p-hydroxybenzoic acid or ester hydrochloride. These compounds inhibit cell wall synthesis by inhibiting the enzyme peptidoglycan synthetase, leading to cell death. Veratric acid has also been shown to increase glomerular filtration rate and improve coordination

• Brand: Biosynth

Chemical properties

• Molecular weight: 182.17 g/mol
• Formula: C₉H₁₀O₄
• Purity: Min. 95%
• Color/Form: White/Off-White Solid
• InChI: InChI=1S/C9H10O4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5H,1-2H3,(H,10,11)
• InChI key: InChIKey=DAUAQNGYDSHRET-UHFFFAOYSA-N
• SMILES: COc1ccc(C(=O)O)cc1OC