D-Valinol

CAS: 4276-09-9

Ref. 3D-FV36829

Product Information

• Name: D-Valinol
• Synonyms: (R)-2-Amino-3-methyl-1-butanolD-D-Val-ol
• Brand: Biosynth
• Description: D-Valinol is a synthetic compound that contains a chiral alcohol group. It is an ester hydrochloride salt of D-valinol and has been shown to be clinically effective in treating chronic lymphocytic leukemia (CLL). This drug is a potent inhibitor of the bcr-abl kinase, which is involved in the regulation of protein synthesis. D-Valinol binds to the kinase domain of this enzyme and inhibits its activity by preventing it from transferring phosphate groups from ATP to tyrosine residues on proteins. D-Valinol also inhibits chloride channels, which are required for cell survival.

Chemical properties

• Molecular weight: 103.16 g/mol
• Formula: C₅H₁₃NO
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3/t5-/m0/s1
• InChI key: InChIKey=NWYYWIJOWOLJNR-YFKPBYRVSA-N
• SMILES: CC(C)[C@@H](N)CO