Vincristine

CAS: 57-22-7

Ref. 3D-FV73877

Product Information

• Name: Vincristine
• Synonyms: (+)-Vincristine, 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv., 22-Oxovincaleukoblastine, 2H-3,7-Methanoazacycloundecino[5,4-b]indole, vincaleukoblastine deriv., Alcrist, Biocristin, Cyctocristine, LCR, Leucristine, Leurocristine, OncoTCS, Oncocristin-AQ, VCR, Vincristin, Vincristina, Vincryst, Vinkristin, Vinlon, Vinstin, HSDB 3199, Vincrystine, NSC 67574, Vincristinum, Vincristine [INN:BAN], UNII-5J49Q6B70F, Vincristinum [INN-Latin], Vincaleukoblastine, 22-oxo-, Vincristina [DCIT], (2ξ,2'β,19ξ)-22-oxovincaleukoblastine, NCI-C04864, CCRIS 5763, NSC-67574, Vincaleukoblastine, 22-oxo-, Onco TCS

Description

Vincristine is a cytotoxic drug that inhibits the growth of tumor cells by interfering with DNA synthesis. It is used to treat various types of cancer, including lymphomas and leukemias. Vincristine has been shown to be effective in treating some infectious diseases, such as malaria and toxoplasmosis. It works by inhibiting the production of methyltransferase, an enzyme that is required for the synthesis of methionine. The long-term toxicity of vincristine has been studied extensively in mice, where it was found to cause congestive heart failure, but not lung tumors. Vincristine also appears to work synergistically with adriamycin in the treatment of squamous carcinoma.

• Brand: Biosynth

Chemical properties

• Molecular weight: 824.96 g/mol
• Formula: C₄₆H₅₆N₄O₁₀
• Purity: Min. 95%
• Color/Form: Powder