Wighteone

CAS: 51225-30-0

Ref. 3D-FW138624

Product Information

• Name: Wighteone
• Synonyms: 5,7,4'-Trihydroxy-6-prenylisoflavoneErythrinin B, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-, 4H-1-benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-, 5,7,4′-Trihydroxy-6-prenylisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one, Erythrinin B

Description

Wighteone is a natural product that inhibits the production of prostaglandin E2 (PGE2) by hl-60 cells. It has been shown to inhibit viral replication in vitro and epidermal growth factor (EGF)-induced proliferation of MCF-7 cells. Wighteone also inhibits mitochondrial membrane potential and increases acetate extract production in mouse tumor cells, which may be due to its ability to modulate the activity of critical enzymes involved in cellular metabolism. Wighteone has been found to be effective against erythromycin-resistant strains of bacteria such as Streptococcus pneumoniae, Enterococcus faecalis, Clostridium perfringens, and Mycobacterium tuberculosis. It has also shown biological activity in mice, including increased fetal bovine serum albumin levels and decreased levels of creatinine kinase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 338.35 g/mol
• Formula: C₂₀H₁₈O₅
• Purity: Min. 95%
• InChI: InChI=1S/C20H18O5/c1-11(2)3-8-14-16(22)9-17-18(19(14)23)20(24)15(10-25-17)12-4-6-13(21)7-5-12/h3-7,9-10,21-23H,8H2,1-2H3
• InChI key: InChIKey=KIMDVVKVNNSHGZ-UHFFFAOYSA-N
• SMILES: CC(C)=CCc1c(O)cc2occ(-c3ccc(O)cc3)c(=O)c2c1O