Xipamide

CAS: 14293-44-8

Ref. 3D-FX28740

Product Information

• Name: Xipamide
• Synonyms: 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide4-Chloro-5-sulfamoyl-2',6'-salicyloxylidideAquaphor, 238-216-4, 2′,6′-Salicyloxylidide, 4-chloro-5-sulfamoyl-, 4-Chloro-5-sulfamylsalicyloyl-2',6'-dimethylanilide, 4-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide, 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxybenzamide, Aquaphor, Aquaphor (diuretic), Be 1293, Bei 1293, Chronexan, Diurex, Diurex (Lacer), Diurexan, Lumitens, Mjf 10938, benzamide, 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-

Description

Xipamide is a dpp-iv inhibitor that functions by blocking the enzyme dipeptidyl peptidase IV (dpp-iv). Xipamide inhibits the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1β) in vitro. It is also effective against infectious diseases, including bacterial infections, respiratory tract infections, and skin infections. Xipamide has been shown to be safe for use in geriatric patients with congestive heart failure. The optimum concentration for xipamide is 0.4 μM. Xipamide has been used to study biological processes such as signal transduction, cell proliferation, and apoptosis in vitro. Optical sensor technology has been applied to examine the stability of this drug in human serum and its potential interactions with surfactant sodium dodecyl sulfate (SDS).

• Brand: Biosynth

Chemical properties

• Molecular weight: 354.81 g/mol
• Formula: C₁₅H₁₅ClN₂O₄S
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)
• InChI key: InChIKey=MTZBBNMLMNBNJL-UHFFFAOYSA-N
• SMILES: Cc1cccc(C)c1NC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1O