Methyl 2-nitropropanoate

CAS: 6118-50-9

Ref. 3D-GAA11850

Product Information

• Name: Methyl 2-nitropropanoate
• Brand: Biosynth
• Description: Methyl 2-nitropropanoate is a reactive compound that is used as an epigenetic marker. It reacts with lysine residues in proteins and histones, resulting in the methylation of these proteins. Methyl 2-nitropropanoate has been shown to inhibit the replication of DNA and induce cellular apoptosis in mammalian cells. The effector proteins H3K9me2 and H4K5me1 are involved in epigenetic changes that include gene silencing and histone demethylation. Methyl 2-nitropropanoate can also cause clastogenic effects by forming adducts on dna replication enzymes, such as amide and demethylation. Histone lysines are methylated by methyl 2-nitropropanoate, which causes histones to condense into tight bundles of DNA that contribute to the formation of actin filaments.

Chemical properties

• Molecular weight: 133.1 g/mol
• Formula: C₄H₇NO₄
• Purity: Min. 95%