Product Information
Name:NSC 45586
Brand:Biosynth
Description:NSC 45586 is an inhibitor of collagenase, which is one of the enzymes that breaks down collagen. It has been shown to have a pharmacodynamic effect on the tibia in rats, and it also has a pharmacokinetic profile similar to other inhibitors of this enzyme. NSC 45586 has a homology domain with proteinases that have been shown to have therapeutic potential for osteoarthritis and rheumatoid arthritis. The drug inhibits the activity of key enzymes involved in cartilage degradation, such as collagenase, proteoglycanase and aggrecanase. It also inhibits phosphatases, which are enzymes that remove phosphate groups from proteins. NSC 45586 can be used intra-articularly or systemically for treatment of osteoarthritic joints by preventing the breakdown of collagen and cartilage.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:413.4 g/mol
Formula:C20H18N6NaO3
Purity:Min. 95%
Technical inquiry about: NSC 45586
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