γ-Lumi (-)-colchicine
CAS: 6901-14-0
Ref. 3D-GAA90114
10mg | 801.00 € | ||
25mg | 1,276.00 € | ||
50mg | 1,739.00 € | ||
100mg | 2,783.00 € |
Product Information
- (7S-(7alpha,7balpha,10aalpha))-N-(5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo(a)cyclopenta(3,4)cyclobuta(1,2-c)cyclohepten-7-yl)acetamide
- Acetamide, N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)-, [7S-(7α,7bα,10aα)]-
- Acetamide, N-[(7S,7bS,10aR)-5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]-
- N-[(7S,7bS,10aR)-1,2,3,9-tetramethoxy-8-oxo-5,6,7,7b,8,10a-hexahydrobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c][7]annulen-7-yl]acetamide
- N-[(7S,7bS,10aR)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide
- γ-Lumicolchicine
- gamma-Lumicolchicine
γ-Lumi (-)-colchicine is a cytotoxic agent that inhibits the activity of the sphingosine-2-phosphate receptor (SP2). It has been used to treat various types of cancer, including mesenchyme cells and leukemia. γ-Lumi (-)-colchicine binds to the 2-adrenergic receptor (AR) in the cytosol, which leads to increased levels of gamma-aminobutyric acid (GABA) and decreased levels of intracellular calcium ions (Ca2+), leading to cell death. γ-Lumi (-)-colchicine has been shown to have clinical relevance in tissue culture experiments.
Chemical properties
Technical inquiry about: 3D-GAA90114 γ-Lumi (-)-colchicine
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