Product Information
Name:1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
Brand:Biosynth
Description:
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one is a potent inhibitor of the enzyme c-glycosylase. This compound has been used in pharmaceutical preparations and as a feedstock in organic syntheses. It is used to produce the anti-inflammatory drug piroxicam, which inhibits the action of cyclooxygenase and blocks the synthesis of prostaglandins. 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one also has been shown to inhibit crystallization of the bovine liver enzyme phosphatidylcholine:cholesterol acyltransferase (PCAT). The inhibition was found to be competitive with respect to PCAT substrate and was not due to inhibition of PCAT by 1,2,4-triazolo[4,3-a]pyridin-3(
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Chemical properties
Molecular weight:135.13 g/mol
Formula:C6H5N3O
Purity:Min. 95%
Technical inquiry about: 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
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