Product Information
FIIN-1 is a non-selective inhibitor of the epidermal growth factor receptor (EGFR). It binds to the EGFR and prevents it from binding with its ligands. This inhibition of EGFR prevents cellular proliferation, which can lead to cancer. FIIN-1 also inhibits the tyrosine kinase activity of the EGFR and therefore inhibits the phosphorylation of proteins that regulate cell growth. FIIN-1 is effective at inhibiting platelet-derived growth factors, such as PDGF, and other growth factors, such as EGF. The binding of FIIN-1 to the EGFR has been shown to inhibit tumor cell proliferation in vitro and in vivo.
Chemical properties
Technical inquiry about: 3D-GAC15235 FIIN-1
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