Product Information
- (±)-2-Phenylpropionic acid methyl ester
- 2-Phenylpropanoic acid methyl ester
- Ai3-07002
- Benzeneacetic acid, alpha-methyl-, methyl ester
- Benzeneacetic acid, α-methyl-, methyl ester
- Hydratropic acid, methyl ester
- Methyl (±)-hydratropate
- Methyl 2-Phenylpropanoate
- Methyl 2-methyl-2-phenylacetate
- Methyl α-methylbenzeneacetate
- See more synonyms
- Methyl α-methylphenylacetate
- Methyl α-phenylpropionate
- Α-Methylbenzeneacetic Acid Methyl Ester
Methyl 2-phenylpropanoate is the product of a lipase-catalyzed reaction between methanol and phenylacetic acid. The hydrolysis of the ester bond releases methanol, which can then react with another molecule of phenylacetic acid to form methyl 2-phenylpropanoate. Methyl 2-phenylpropanoate is a key intermediate in the synthesis of beta blockers, such as propranolol. It can also be used as an alternative to cyclopentane for synthesizing stereoisomers of cyclohexane. The reaction mechanism involves an activation energy that is kinetically favorable and has an asymmetric synthesis. The stereoselectivity of this reaction is due to the use of an acid catalyst and a chiral ligand.
Chemical properties
Technical inquiry about: 3D-GBA50844 Methyl 2-phenylpropanoate
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