Product Information
Name:(3β,25S)-Cholest-5-ene-3,26-diol
Controlled Product
Brand:Biosynth
Description:(3β,25S)-Cholest-5-ene-3,26-diol is a stereogenic cholestanol analog that has been synthesized by saponification of (3β,25R)-cholestanol. It has been shown to induce osteolysis in the worm Caenorhabditis elegans in vitro and in vivo. The compound has also been shown to be biologically active against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. The effects of (3β,25S)-cholest-5-ene-3,26-diol on bone resorption are stereoselective. In contrast to other cholestanol analogs that have been studied, it does not bind to the bile acid receptor but instead binds to the nuclear receptor farnesoid X receptor (FXR). As a result, it does not cause elevated serum levels
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Chemical properties
Molecular weight:402.7 g/mol
Formula:C27H46O2
Purity:Min. 95%
Technical inquiry about: (3β,25S)-Cholest-5-ene-3,26-diol
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