Methyl 5-methyl-4-nitrothiophene-2-carboxylate
CAS: 56921-01-8
Ref. 3D-GCA92101
| 50mg | 187.00 € | ||
| 500mg | 746.00 € |
Product Information
Methyl 5-methyl-4-nitrothiophene-2-carboxylate (MMTC) is a potent and selective inhibitor of the RNA polymerase. MMTC inhibits the replication of both single stranded and double stranded RNA viruses, such as hepatitis C virus (HCV), human immunodeficiency virus (HIV), and influenza. MMTC is an allosteric inhibitor that binds to the active site of the polymerase at a specific site, which prevents it from binding to its natural substrate, rRNA. This binding prevents elongation of the RNA chain by interfering with nucleotide addition, leading to termination of RNA synthesis. MMTC also inhibits replication of subgenomic RNAs in HCV and HIV infection.
Chemical properties
Technical inquiry about: 3D-GCA92101 Methyl 5-methyl-4-nitrothiophene-2-carboxylate
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