Product Information
Name:U 46619
Brand:Biosynth
Description:U 46619 is an analog of the peptide neurotransmitter acetylcholine. It is a potent and specific agonist for the nicotinic acetylcholine receptor (nAChR) in cardiac muscle cells. U 46619 binds to the cation channel on the nAChR, leading to changes in membrane potential and increased calcium influx. This drug has been shown to have positive effects on ventricular myocytes by increasing whole-cell voltage-clamp currents in rat cardiomyocytes. The biological properties of U 46619 have been investigated using an experimental model with maternal blood as a source of antibodies against acetylcholine, which was used to detect binding of radioactively labeled U 46619 to the receptors in the blood serum. Clinical studies have demonstrated that this drug may be useful for treating patients with heart failure or arrhythmias.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:350.5 g/mol
Formula:C21H34O4
Purity:Min. 95%
Technical inquiry about: U 46619
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