Product Information
5-Methyl-1H-indazol-4-amine is a tyrosine kinase inhibitor that has been shown to be potent in inhibiting the activity of various types of tyrosine kinases. It has good oral pharmacokinetics and is not metabolized by the liver. 5-Methyl-1H-indazol-4-amine binds to the ATP site on the enzyme and prevents phosphorylation, which inhibits cell proliferation and growth. This agent also inhibits DNA synthesis, protein synthesis, and phosphoinositide turnover in cells. 5-Methyl-1H-indazol-4-amine is an orally active inhibitor of tyrosine kinases with good oral pharmacokinetics and does not require metabolic activation by the liver. This agent may be used for the treatment of cancer or other diseases associated with uncontrolled cell growth.
Chemical properties
Technical inquiry about: 3D-GDA11560 5-Methyl-1H-indazol-4-amine
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