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Product Information
- St 271
- (2E)-2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]prop-2-enamide
ST271 is a novel, potent and selective inhibitor of bacterial DNA-dependent RNA polymerase. It has been shown to be active against Gram-positive bacteria that are resistant to ceftriaxone and erythromycin, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). ST271 blocks the synthesis of proteins by inhibiting the enzyme ribosome. This drug also has anti-inflammatory properties, which may be due to its ability to inhibit epidermal growth factor receptor phosphorylation.
Chemical properties
Technical inquiry about: 3D-GEA39248 ST271
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