Product Information
Name:PS-1145
Synonyms:
- N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
Brand:Biosynth
Description:PS-1145 is a chemical inhibitor that belongs to the class of small molecule inhibitors. PS-1145 binds to the IL2 receptor and blocks the activation of BCL-2 protein, leading to cell death by inhibiting the production of proteins vital for cell division. It also inhibits inhibitory proteins such as IκBα and NEMO, which are important for NF-κB signaling. PS-1145 induces oxidative injury and caspase-independent cell death in cells by binding to DNA at response elements, thereby inhibiting transcriptional activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:322.75 g/mol
Formula:C17H11ClN4O
Purity:Min. 95%
Technical inquiry about: PS-1145
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