2-(2,4-Dichlorophenyl)-2-hydroxyacetic acid

CAS: 7554-78-1

Ref. 3D-HAA55478

Product Information

• Name: 2-(2,4-Dichlorophenyl)-2-hydroxyacetic acid
• Synonyms: NSC 409412, Mandelic acid, 2,4-dichloro-, 3-10-00-00479 (Beilstein Handbook Reference), 2,4-Dichloro-alpha-hydroxybenzeneacetic acid, NSC 409412, Mandelic acid, 2,4-dichloro-, 2,4-Dichloro-α-hydroxybenzeneacetic acid, Benzeneacetic acid, 2,4-dichloro-α-hydroxy-, 2,4-Dichloromandelic acid, BRN 2728753, (2,4-dichlorophenyl)(hydroxy)acetic acid, 2,4-Dichloromandelic acid, Benzeneacetic acid, 2,4-dichloro-alpha-hydroxy- (9CI)

Description

2-(2,4-Dichlorophenyl)-2-hydroxyacetic acid (dichlophos) is a metabolite of the herbicide 2,4-dichlorophenoxyacetic acid. It is spontaneously generated in the cytosol and eliminated in the urine as its conjugate with glutathione. Dichlophos has been shown to inhibit the activity of glutathione transferase, which may be due to its ability to demethylate phospholipids and glutathione. Dichlophos has also been found to have an inhibitory effect on alkenyl and ketone metabolism, which may be due to its ability to block hydrogen phosphate synthesis. This compound has been shown to be metabolized by uronic acid oxidase in rats and humans, leading to the production of 2-keto-gluconic acid and hydrogen peroxide.

• Brand: Biosynth

Chemical properties

• Molecular weight: 221.03 g/mol
• Formula: C₈H₆Cl₂O₃
• Purity: Min. 95%