Product Information
- 3,5-Dinitro-1,2-benzenediol
- 3,5-Dinitrocatechol
- 1,2-Benzenediol, 3,5-dinitro-
- Pyrocatechol, 3,5-dinitro-
- 3,5-Dinitropyrocatechol
OR-486 is a basic dye with pharmacological properties. It has been shown to have low-energy fluorescence, and it can be used for the detection of dopamine. OR-486 can also inhibit catechol-o-methyltransferase (COMT), an enzyme that catalyzes the methylation of catecholamines, including dopamine and epinephrine. In addition, OR-486 inhibits xanthine oxidase (XO) in vitro and in vivo. It has been shown to be effective against diabetic neuropathy in Sprague-Dawley rats as well as deficient mice. OR-486 has also been shown to increase the uptake of glucose by cells in a plate test.
Chemical properties
Technical inquiry about: 3D-HAA65929 OR-486
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