5-(Bromomethyl)-1,3-dichlorobenzene

CAS: 7778-01-0

Ref. 3D-HAA77801

Product Information

• Name: 5-(Bromomethyl)-1,3-dichlorobenzene
• Brand: Biosynth
• Description: 5-(Bromomethyl)-1,3-dichlorobenzene is a lead compound for the treatment of osteoarthritis. It inhibits aggrecanase and proteoglycanases, which are enzymes that break down proteins in cartilage. 5-(Bromomethyl)-1,3-dichlorobenzene has been shown to inhibit mmp-1 and tnf-α and to be selective for aggrecanase over other proteoglycanases. This drug also has anti-inflammatory properties due to its ability to inhibit cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 5-(Bromomethyl)-1,3-dichlorobenzene is a racemic mixture of two enantiomers (enantiomer 1 and enantiomer 2). Enantiomer 1 is more potent than enantiomer 2 at inhibiting aggrecanase and proteoglycanases.

Chemical properties

• Molecular weight: 239.93 g/mol
• Formula: C₇H₅BrCl₂
• Purity: Min. 95%