Product Information
ML289 is an allosteric modulator of metabotropic glutamate receptors (mGluRs). It has been shown to activate mGluR2/3 and mGluR4 in vitro. ML289 is a structural analog of the amino acid glutamate and binds to the same site as glutamate. This binding leads to increased signaling through these receptors, which are involved in many physiological processes, including myotonica and physiochemical functions. ML290 has been shown to be penetrant in vivo, with high brain concentrations achieved following peripheral administration. The pharmacokinetics of ML290 have also been characterized in rats, demonstrating that it is rapidly absorbed after oral administration and its concentration remains relatively stable over time.
ML290 has also been shown to bind metal surfaces such as steel or nickel, making it a potential candidate for use on metal surfaces where bacteria may grow.
Chemical properties
Technical inquiry about: 3D-HFC48179 ML289
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