Product Information
- Coronarin Dmethyl ether
Coronarin D methyl ether is a diterpene with the chemical structure of (2E,4E,6E)-3,7-dimethylocta-2,6-dienal. It has been shown to inhibit inflammatory cytokines such as TNF-α and IL-1β in human lung cells and rhizomes. Coronarin D methyl ether has also been shown to have significant cytotoxicity against leukemia cells and MM cells. The molecular docking analysis of coronarin D methyl ether and its target protein NFκB showed that coronarin D methyl ether binds to the DNA binding domain of NFκB. This binding inhibits the transcription of pro-inflammatory cytokine genes, leading to inhibition of inflammation.
Chemical properties
Technical inquiry about: 3D-HGA52881 Coronarin D methyl ether
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