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IR-780 iodide
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IR-780 iodide

CAS: 207399-07-3

Ref. 3D-HIA39907

250mg
290.00 €
2500mg
1,102.00 €
Estimated delivery in United States, on Thursday 23 Jan 2025

Product Information

Name:
IR-780 iodide
Synonyms:
  • 2-[(Z)-2-{(3E)-2-chloro-3-[(2E)-2-(3,3-dimethyl-1-propyl-1,3-dihydro-2H-indol-2-ylidene)ethylidene]cyclohex-1-en-1-yl}ethenyl]-3,3-dimethyl-1-propyl-3H-indolium iodide
  • 3H-Indolium, 2-(2-(2-chloro-3-((1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl)ethenyl)-3,3-dimethyl-1-propyl-, iodide
  • 3H-Indolium, 2-(2-(2-chloro-3-(2-(1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl)ethenyl)-3,3-dimethyl-1-propyl-, iodide (1:1)
  • Ads 775Pi
  • Ir 780
  • IR 780 iodide
Description:

IR-780 iodide is a water-soluble drug that has been shown to have significant cytotoxicity against prostate cancer cells. It binds to the mitochondrial membrane potential, which is involved in energy production and the regulation of the cell cycle. IR-780 iodide is taken up by tumor cells, where it inhibits adriamycin uptake and induces apoptosis. In vitro assays have shown that IR-780 iodide can be used as a diagnostic tool for detecting bladder cancer by binding to the mitochondria of cells from patients with bladder cancer. In vivo studies have been done in mice to determine the effectiveness of IR-780 iodide in treating cervical cancer. These studies showed that IR-780 iodide was not significantly effective in vivo, due to its low bioavailability and lack of specificity for cervical cancer cells. Histological analysis showed that IR-780 iodide did not inhibit tumor growth or induce apoptosis in vivo.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
667.11 g/mol
Formula:
C36H44ClIN2
Purity:
Min. 95%
MDL:
Melting point:
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Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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