Product Information
PF 04447943 is a small-molecule, orally bioavailable drug with potential for the treatment of inflammatory bowel disease (IBD). PF 04447943 is a potent inhibitor of TNF-α, which is involved in the pathogenesis of IBD. This compound has been shown to have statistically significant efficacy in wild-type mice and to have low expression in human nuclear DNA. The onset latency of this drug is approximately one week. PF 04447943 inhibits NF-κB and other signal pathways that are involved in the inflammatory response. It also inhibits glutamate dehydrogenase and has shown activity against natural compounds in vitro.
Chemical properties
Technical inquiry about: 3D-HTB74420 PF 04447943
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