Product Information
Name:THK5351
Brand:Biosynth
Description:THK5351 is a high-affinity ligand for amyloid beta precursor protein (APP) and is used in positron emission tomography (PET) scans to diagnose Alzheimer's disease. It is a peptide that binds to the acid complex of APP, which is thought to be associated with the reactive form of the protein. THK5351 has been shown to bind specifically to the pathological form of APP, but not to normal APP. THK5351 has been shown in clinical studies to have an uptake in the brain's ganglia and cerebral cortex, areas associated with Alzheimer's disease pathology. Molecular modeling studies have shown that THK5351 binds to APP by binding at a site between two amino acids known as K16 and K17. This binding prevents formation of an amyloid beta peptide that can aggregate into plaques.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:327.4 g/mol
Formula:C18H18FN3O2
Purity:Min. 95%
Technical inquiry about: THK5351
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