Product Information
Name:5-Amino-2-(3-oxo-4-morpholinyl)benzonitrile
Brand:Biosynth
Description:5-Amino-2-(3-oxo-4-morpholinyl)benzonitrile (5ABA) is a potent, selective, and noncompetitive inhibitor of the ion channel TASK1. 5ABA inhibits the activation of TASK1 by interacting with the binding site for the activator protein, calcitonin gene-related peptide (CGRP). It has been shown that 5ABA inhibits CGRP-induced currents in rat sensory neurons in a dose dependent manner. This activity is specific to TASK1 channels, as it does not inhibit other members of the K+ channel superfamily.
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Chemical properties
Molecular weight:217.22 g/mol
Formula:C11H11N3O2
Purity:Min. 95%
Technical inquiry about: 5-Amino-2-(3-oxo-4-morpholinyl)benzonitrile
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