(S)-AntPhos

Ref. 3D-HXC74034

Product Information

• Name: (S)-AntPhos
• Brand: Biosynth
• Description: (S)-AntPhos is a ligand with a high affinity for metal ions and the ability to hydrolyze esters. It has been used in buchwald-type reactions, which are enantioselective coupling reactions. This ligand can be used as an alternative to BINAP in Buchwald-Hartwig reactions by forming a chiral phosphine complex with the alkyne and mesembrine, which is then coupled with an electrophile. The use of (S)-AntPhos provides access to enantioenriched products that cannot be obtained using other methods. One example of such a reaction is the synthesis of (+)alpha-methylbenzyl alcohol from (+)alpha-methylstyrene and methanol. The use of (S)-AntPhos was found to increase the yield of the desired product by up to 10% compared to other ligands.

Chemical properties

• Molecular weight: 370.42 g/mol
• Formula: C₂₅H₂₃O₃P
• Purity: Min. 95%