Product Information
Name:NVS-CRF-38
Brand:Biosynth
Description:NVS-CRF-38 is a corticotropin-releasing factor (CRF) analog. It is a conjugated form of the CRF-III peptide, which has been modified to contain a phenylalanine residue at position 3 and an arginine residue at position 9. The test compound binds to the CRF receptor and acts as a partial agonist. NVS-CRF-38 has been shown to have pharmacokinetic properties similar to those of native CRF in rats and humans. In rats, plasma protein binding was ˜80% with no effect by deuterium isotope on drug pharmacokinetics. In humans, it was found that NVS-CRF-38 had high oral bioavailability and good absorption in the small intestine.
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Chemical properties
Molecular weight:351.4 g/mol
Formula:C19H21N5O2
Purity:Min. 95%
Technical inquiry about: NVS-CRF-38
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