Product Information
BI-847325 is a new compound that inhibits the expression of genes that are involved in the development of cancer. It has been shown to have a potent inhibitory effect on cell proliferation and pro-apoptotic protein. BI-847325 is orally active, crossing the blood brain barrier in animals, and has a low toxicity profile. BI-847325 inhibits RNA synthesis by binding to the enzyme rRNA polymerase or by inhibiting ribosome activity. This compound also inhibits ATP levels and replication of DNA in liver cells, which may be due to its ability to bind to metagene sequences. BI-847325 has demonstrated promising results in animal studies for gastrointestinal toxicities, with no evidence of weight loss or anorexia at doses up to 15 times higher than the dose required for efficacy against cancer cells.
Chemical properties
Technical inquiry about: 3D-HYB29336 BI-847325
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