Product Information
Name:FRAX486
Synonyms:
- 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
Brand:Biosynth
Description:FRAX486 is a kinase inhibitor that binds to the ATP-binding site of the epidermal growth factor receptor (EGFR) and prevents it from binding to ATP. The EGFR is involved in signaling pathways that are important for cell proliferation, differentiation, and survival. FRAX486 is selective for EGFR over other members of the tyrosine kinase family, such as CDK4/6. This drug has been shown to inhibit tumor growth by inducing apoptosis in mutant melanoma cells and inhibiting their migration. It also inhibits the phosphorylation of actin filaments and reduces bladder inflammation.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:513.4 g/mol
Formula:C25H23Cl2FN6O
Purity:Min. 95%
Technical inquiry about: FRAX486
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