Aztreonam impurity D

CAS: 102579-59-9

Ref. 3D-IA167738

Product Information

• Name: Aztreonam impurity D
• Synonyms: Desulfo aztreonam
• Brand: Biosynth
• Description: Aztreonam impurity D is a metabolite of aztreonam. Aztreonam impurity D is an impurity standard for the pharmacopoeia and API industry, as well as for drug development and research. It has been shown that this compound inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Aztreonam impurity D also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Chemical properties

• Molecular weight: 355.37 g/mol
• Formula: C₁₃H₁₇N₅O₅S
• Purity: Min. 95 Area-%
• Color/Form: Powder