Aceclofenac benzyl ester

CAS: 100499-89-6

Ref. 3D-IA16909

Product Information

• Name: Aceclofenac benzyl ester
• Synonyms: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid 2-oxo-2-(phenylmethoxy)ethyl esterAceclofenac impurity F
• Brand: Biosynth
• Description: Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the propionic acid derivative group. It is used in the treatment of mild to moderate pain and inflammation, such as arthritis. Aceclofenac is rapidly hydrolyzed by esterases in the small intestine, resulting in the release of aceclofenac acid. Aceclofenac benzyl ester is a chemical intermediate that has been shown to be an efficient method for producing aceclofenac acid. It can be obtained by reacting bromoacetic anhydride with methyl alcohol and then hydrolyzing the product with strong acids. This compound may contain impurities, such as nucleophilic impurities, which can lead to side effects.

Chemical properties

• Molecular weight: 444.31 g/mol
• Formula: C₂₃H₁₉Cl₂NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C23H19Cl2NO4/c24-18-10-6-11-19(25)23(18)26-20-12-5-4-9-17(20)13-21(27)30-15-22(28)29-14-16-7-2-1-3-8-16/h1-12,26H,13-15H2
• InChI key: InChIKey=RLKZSYGBKCIRFJ-UHFFFAOYSA-N
• SMILES: O=C(COC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl)OCc1ccccc1