Apixaban Impurity 1
CAS: 503614-91-3
Ref. 3D-IA176149
1kg | 1,160.00 € | ||
50g | 172.00 € | ||
100g | 271.00 € | ||
250g | 469.00 € | ||
500g | 740.00 € |
Product Information
- 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, ethyl ester
- Apixaban ethyl ester
- Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Apixaban Impurity 1 is an impurity found in Apixaban, a drug used for the prevention of stroke. It is produced by condensation of 2-aminopyridine and 3-hydroxybenzaldehyde in ethanol with sodium hydroxide as a catalyst. The reaction proceeds via amination of the pyridine ring followed by transesterification. The yield of this impurity is low at about 4%.
Chemical properties
Technical inquiry about: 3D-IA176149 Apixaban Impurity 1
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