Anastrozole dimer impurity

CAS: 1216898-82-6

Ref. 3D-IA17900

Product Information

• Name: Anastrozole dimer impurity
• Synonyms: 2,3-Bis[3-(1-cyano-1-methylethyl)-5-(1H,1,2,3-triazole-1-ylmethyl)phenyl]-2-methylpropionitrileAnastrozole impurity C
• Brand: Biosynth
• Description: Anastrozole is an aromatase inhibitor that has been used in the treatment of breast cancer. It binds competitively to the heme moiety of aromatase, blocking its access to substrate and thereby inhibiting estrogen production. Anastrozole dimer impurity is an analytical impurity found in drug products that is not a natural component of the API (active pharmaceutical ingredient). CAS No. 1216898-82-6 refers to this impurity standard as well as other synthetic analogues. This impurity is a custom synthesis with no pharmacopoeia standards for purity. The HPLC standard for this product is high purity (99%).

Chemical properties

• Molecular weight: 517.63 g/mol
• Formula: C₃₀H₃₁N₉
• Purity: Min. 95%
• SMILES: CC(C)(C#N)c1cc(Cn2cncn2)cc(CC(C)(C#N)c2cc(Cn3cncn3)cc(C(C)(C)C#N)c2)c1