trans-4-(Aminomethyl)cyclohexanecarboxylic acid

CAS: 1197-17-7

Ref. 3D-IA71533

Product Information

• Name: trans-4-(Aminomethyl)cyclohexanecarboxylic acid
• Synonyms: Tranexamic acid impurity Bcis-Tranexamic acid, Tranexamic acid cis-form, cis-AMCHA, cis-4-(Aminomethyl)cyclohexanecarboxylic acid, 4-(Aminomethyl)Cyclohexane-1-Carboxylic Acid, cis-4-Aminomethylcyclohexane-1-carboxylic acid

Description

Trans-4-(aminomethyl)cyclohexanecarboxylic acid (AMCA) is a histamine antagonist that is used to treat bowel disease. It may also be useful for the treatment of other inflammatory diseases and as an anticoagulant. AMCA has been shown to be safe and effective for the prevention of postoperative bleeding in patients who are undergoing major surgery. This drug is a potent inhibitor of platelet aggregation, but does not affect the function of erythrocytes or leukocytes. AMCA inhibits platelet aggregation by blocking the binding of adenosine diphosphate (ADP) to its receptor on platelets, thus inhibiting ADP-mediated activation of phospholipase A2 and arachidonic acid release from membranes. An increase in blood levels of AMCA may lead to cardiac toxicity and bleeding events.

• Brand: Biosynth

Chemical properties

• Molecular weight: 157.21 g/mol
• Formula: C₈H₁₅NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)
• InChI key: InChIKey=GYDJEQRTZSCIOI-UHFFFAOYSA-N
• SMILES: NCC1CCC(C(=O)O)CC1