Product Information
Name:ACT-389949
Brand:Biosynth
Description:ACT-389949 is a novel small molecule that has been shown to be a potent inhibitor of neutrophil recruitment. It has been shown to inhibit the chemotaxis of neutrophils and leukocytes in vitro by binding to granule proteins and preventing their release. ACT-389949 is an orally active, potent, selective, and reversible inhibitor of neutrophil recruitment with a terminal half-life of approximately 24 hours. The pharmacodynamics of this drug are dose-dependent with an EC50 value at the lower end of the therapeutic window. This profile may explain why it is effective in patients who have been exposed to other drugs that are ineffective due to resistance. In addition, ACT-389949 does not induce any known inflammatory cytokines or act as an immunosuppressant.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:428.4 g/mol
Formula:C20H18F2N6O3
Purity:Min. 95%
Technical inquiry about: ACT-389949
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