8-Chloro-2H-chromen-2-one

Ref. 3D-IBA49129

Product Information

• Name: 8-Chloro-2H-chromen-2-one
• Brand: Biosynth
• Description: 8-Chloro-2H-chromen-2-one is a small molecule that acts as a protein kinase inhibitor. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo, including mammary cancer cells and cervical cancer cells. 8-Chloro-2H-chromen-2-one inhibits the tumorigenic properties of mcf-7 cells by blocking mitogenic signaling pathways, specifically the phosphorylation of pRb by protein kinase B (PKB). This compound also has antitumor activity against both cultured cell lines and xenografts, inhibiting tumor growth in nude mice.

Chemical properties

• Molecular weight: 180.59 g/mol
• Formula: C₉H₅ClO₂
• Purity: Min. 95%