Product Information
- 1,3-Benzenedicarboxylic acid, mono(1,1-dimethylethyl) ester
- 3-(tert-Butoxycarbonyl)benzoic acid
3-(tert-Butoxycarbonyl)benzoic acid is a pro-apoptotic agent that binds to the cytosolic domain of Bcl-xL and Bcl-2, causing the release of cytochrome c from mitochondria. This drug also inhibits the proliferation of tumor cells in culture with an IC50 value of about 2 μM. The crystal structure of 3-(tert-Butoxycarbonyl)benzoic acid has been determined by x-ray crystallography and shows that it has antiproliferative activity. It is an optimized analog for bcl-xl, which could be used as a potential cancer chemotherapeutic agent.
Chemical properties
Technical inquiry about: 3D-IBA70419 3-(tert-Butoxycarbonyl)benzoic acid
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