N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide

CAS: 90357-51-0

Ref. 3D-IC58274

Product Information

• Name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
• Synonyms: N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxideBicalutamide epoxide impurity, 1,2-Epoxy-2-Methyl-N-[4-Cyano-3-(Trifluoromethyl)], 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide, 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethylphenyl)-amide, 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide, 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-, 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide, Carboxamide, N-[4-Cyano-3-(Triflouromethyl)Phenyl]-2-Methyl-2-Oxirane Carboxamide, N-[4-Cyano-3-(Trifluoromethyl)Phenyl]Methacrylamide Epoxide, N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide, N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide, N-[4-Cyano-3-Trifluoromethy Phenyl]-2-Oxirane Carboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide, Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-, Phenyl]-2-methyl-2-oxirane, n-[4-cyano-3-(triflouromethyl)
• CAS: 90357-51-0

Description

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.

• Brand: Biosynth

Chemical properties

• Molecular weight: 270.21 g/mol
• Formula: C₁₂H₉F₃N₂O₂
• Purity: Min. 95%
• Color/Form: White Powder
• SMILES: CC1(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)CO1