Cisplatin impurity A

CAS: 14913-33-8

Ref. 3D-IC63739

Product Information

• Name: Cisplatin impurity A
• Synonyms: Transplatin, (SP-4-1)-Diamminedichloroplatinum, Diamminedichloro-Platinu(Sp-4-1), Dichlorodiamineplatinum(Ii), NSC 131558, Nsc131558, Platinum(2+) Chloride Ammoniate (1:2:2), Platinum(4+) Chloride Azanide (1:2:2), Platinum, diamminedichloro-, (SP-4-1)-, Platinum, diamminedichloro-, trans-, Trans-Diaminedichloroplatinum, Trans-Diamminedichloroplatinum, Trans-Dichlorodiammineplatinum, Trans-Platinumdiamminedichloride, trans-DDP, trans-Diamminedichloroplatinum(II), trans-Dichlorodiammine platinum, trans-Dichlorodiammineplatinum(II), trans-Platinum(II) ammonium chloride, trans-Platinumdiammine dichloride

Description

Cisplatin impurity A is a platinum-based chemotherapeutic agent that binds to DNA and inhibits the synthesis of cellular proteins. Cisplatin impurity A has been shown to inhibit the growth of cancer cells in vitro and in vivo. This compound also inhibits the production of epidermal growth factor, which may be due to its ability to bind dna at tetrazolium dye adducts. The coordination geometry of cisplatin impurity A is octahedral with two axial bidentate chelating ligands, which allows it to bind both DNA and tubule cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 300.05 g/mol
• Formula: (NH₃)₂Cl₂Pt
• Color/Form: Powder