Chlorthalidone impurity A

CAS: 5270-74-6

Ref. 3D-IC75148

Product Information

• Name: Chlorthalidone impurity A
• Synonyms: 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]benzoic acid4?-Chloro-3?-sulfamoyl-2-benzophenone-2-carboxylic acid, 2-(4-Chloro-3-Sulfamoylbenzoyl)Benzoic Acid, 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]benzoic acid, Benzoic acid, 2-[3-(aminosulfonyl)-4-chlorobenzoyl]-, Benzoic acid, o-(4-chloro-3-sulfamoylbenzoyl)-, 2-(4-Chloro-3-sulphamoylbenzoyl)benzoic acid

Description

Chlorthalidone impurity A is an impurity in Chlorthalidone. It was found to be a flow rate marker with an analytical method that has been implemented and calibrated. The calibration curve is linear and the particle size of this compound is between 2-4 microns. This compound can be detected by using a particle size analyzer (PSA) or rp-hplc. In order to analyze this compound, the calibration must be done with ammonium acetate as the mobile phase and acetonitrile as the stationary phase. The wavelength for detection is 220 nm and the runtime is 1 minute. Analytical methods such as chromatographic methods, ultraviolet spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectroscopy may also be used to identify this compound.

• Brand: Biosynth

Chemical properties

• Molecular weight: 339.75 g/mol
• Formula: C₁₄H₁₀ClNO₅S
• Purity: Min. 95%
• InChI: InChI=1S/C14H10ClNO5S/c15-11-6-5-8(7-12(11)22(16,20)21)13(17)9-3-1-2-4-10(9)14(18)19/h1-7H,(H,18,19)(H2,16,20,21)
• InChI key: InChIKey=UKRADWWBRBBJLZ-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1cc(C(=O)c2ccccc2C(=O)O)ccc1Cl