Product Information
- Acetamide, 2-(2-nitrophenoxy)-
- Acetamide, 2-(o-nitrophenoxy)-
- 2-(Carbamoylmethoxy)nitrobenzene
2-(2-Nitrophenoxy)acetamide (NPA) is a nitro-substituted nitroaromatic compound that has been shown to inhibit the activity of the P-glycoprotein efflux pump. This inhibitory effect may be due to its ability to bind to the ATP binding site on the P-glycoprotein, which prevents ATP hydrolysis and energy transfer. 2-(2-Nitrophenoxy)acetamide also inhibits cancer cells, as it utilizes adenosine triphosphate (ATP) as an energy source. NPA also displays an inhibitory effect on other cellular functions, including transport of substances across membranes and inhibition of DNA synthesis in human cells.
Chemical properties
Technical inquiry about: 3D-ICA56246 2-(2-Nitrophenoxy)acetamide
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