Product Information
- (Z) - 2- (4- (4- Chloro- 1
- 2- diphenylbut- 1- en- 1- yl) phenoxy) - N- methylethan- 1- amine
- 2-(4-((1Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)-N-methylethanamine
- N-Demethyltoremifene
- Ethanamine, 2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-N-methyl-, (Z)-
- 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N-methylethanamine
N-Desmethyltoremifene is an anti-estrogen that has been shown to have genotoxic effects. It inhibits DNA synthesis and protein synthesis in human breast cancer cells. N-Desmethyltoremifene is a potent inducer of CYP3A4, which metabolizes many drugs. This drug also binds to α1-acid glycoprotein, which can lead to reduced plasma concentrations and pharmacokinetics. N-Desmethyltoremifene has been shown to inhibit the growth of renal cell carcinoma in animals, but not normal tissue, at high doses.
Chemical properties
Technical inquiry about: 3D-ID158043 N-Desmethyltoremifene
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