13-O-Desmethyl tacrolimus
CAS: 139958-51-3
Ref. 3D-ID161984
| 1mg | 341.00 € | ||
| 2mg | 453.00 € | ||
| 5mg | 711.00 € | ||
| 10mg | 1,047.00 € | ||
| 25mg | 1,971.00 € |
Product Information
Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.
Chemical properties
Technical inquiry about: 3D-ID161984 13-O-Desmethyl tacrolimus
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